宿主 |
Mouse |
英文名称 |
Anti-ACE Monoclonal Antibody |
别名 |
ACE1;CD143;DCP;DCP1;Angiotensin Converting Enzyme 1 |
稀释比例 |
WB 1:1000. |
蛋白分子量 |
79/83/132/150kDa |
Gene ID |
1636 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG2a |
免疫原 |
Purified recombinant human Angiotensin Converting Enzyme 1 protein fragments expressed in E.coli. |
性状 |
液体 |
Public Immunogen Range |
Purified recombinant human Angiotensin Converting Enzyme 1 protein fragments expressed in E.coli. |
亚细胞定位 |
Cell membrane Cytoplasm Secreted Single-pass type I membrane protein |
Swiss Prot |
P12821 |
克隆号 |
4F3-E6-H8 |
克隆类型 |
Monoclonal Antibody |
背景资料 |
This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined. |
应用 |
WB |
交叉反应 |
Mouse |